Eye Didn't Know!

Longer, Thicker, Darker Eyelashes With Latisse®

Did you know? Latisse® is the new prescription medicine for growing longer, thicker eyelashes. Patients are already coming to my office and asking for it. The aesthetician in my office has been using it for a number of weeks and already reports a noticeable difference in her eyelashes.

Latisse® was developed because of a side-effect of a commonly used eyedrop for glaucoma. I can always tell if these patients are using their drops because their lashes are thicker and longer! Allergan decided to reformulate this medicine into a liquid which can be applied to the base of the upper eyelashes. In their clinical trial of 278 patients, 79% of patients noted thicker, longer and darker lashes at week 20 compared to 20% using a placebo. The majority noted improvement after two months. 

The eyelashes gradually return to their baseline appearance after discontinuing the medicine.

There is a theoretical side-effect of permanent darkening of the iris (the eye color), though this did not happen in the clinical trial, and is unlikely to occur if the medicine does not enter the eye. There is also the theoretical side-effect of reversible skin darkening, but this did not occur in the trial either.

Did you also know? Allergan, the makers of Latisse®, also make BOTOX® and Juvederm®. I enjoy using all of these products in my practice, and my patients enjoy looking younger, with a natural appearance.

Macular Degeneration and Cataract Surgery

Did you know? For many years it has been controversial whether having cataract surgery could accelerate the development of advanced macular degeneration. Some patients have cataract surgery, and not long after, develop worsening of their macular degeneration. Patients, of course, will often blame the cataract surgery. (I have at least one patient who falls into that category). What confounds this logic, though, is that cataracts occur with aging, as does macular degeneration. Patients may experience macular degeneration worsening with or without having had cataract surgery.

At last a well-designed study has addressed this question. The Age-Related Eye Disease Study (AREDS) was conducted between 1992 and 2005 and followed over 8,000 eyes of over 4,000 patients. The study was designed to assess the effect of antioxidants and mineral supplements on macular degeneration. The study assessed the development of advanced macular degeneration and history of cataract surgery at six month intervals during the study.

The results showed that appromately 20% of the eyes underwent cataract surgery during the study. Of the eyes undergoing surgery, 6% developed severe macular degeneration. Of the eyes not undergoing surgery, 7% developed severe macular degeneration. The results of the two groups did not significantly differ statistically.

It can be safely said that modern cataract surgery in unlikely to be related to worsening of macular degeneration.

Did you also know? The AREDS study originally found that their combination of zinc and antioxidants (now found in Ocuvite and others) modestly reduced the risk of progression for eyes with early signs of macular degeneration. The AREDS II study, ongoing now, is investigating the possible roles of omega-3 fatty acids, lutein, and zeaxanthin. It is also investigating if the dosage of zinc can be reduced and whether beta-carotene can be eliminated (for safety reasons in some patients).