Beta Carotene and Macular Degeneration

Did you know? A new study has been released in Archives of Ophthalmology, which followed over 22,000 male physicians for twelve years. Half were randomized to take beta-carotene supplementation, half took a placebo. There was NO statistical difference in the incidence of macular degeneration between the two groups. Supplementation had neither a beneficial or harmful effect. This study is notable in its rigorous design, number of subjects, and length of follow-up. The authors are among the most respected in the field of ocular epidemiology.

Did you also know? The well-known AREDS study looked at supplementation with high doses of zinc, beta-carotene, and vitamins C and E. This study showed a modest benefit for those with a high-risk of macular degeneration, (those with significant drusen in their maculas), but no measurable effect for those with no risk factors, since the risk for these patients was low to begin with.